Looking for Lepidic Component inside Invasive Adenocarcinomas Appearing as CT Solid Solitary Pulmonary Nodules (SPNs): CT Morpho-Densitometric Features and 18-FDG PET Findings

Table 2

Imaging parameters and significant statistical tests. The table shows the main results of imaging analysis expressed as the mean value and standard deviation (SD) for continuous variables and as percentage for categorical variables. For statistical tests, a p-value < 0.05 was considered significant.

Parameters	Mean ± SD	Correlation
Maximum diameter (Dmax)	15.45 ± 2.58	Dmax / SUVmax: R = 0.501
CE	53.34 ± 31.49	SUVmax/Lobulated: R = 0.455
SUVmax	2.21 ± 2.15
Morphologic parameters		Hypothesis	p-value
Spiculated margins (SpM)	40.91	Spicules (40.91%) vs. SmM (9.09%)	0.0195 (M)
Lobulated margins (LM)	27.27	SpM (40.91%) vs. SmM (9.09%)	0.0327 (M)
Irregular margins (IM)	27.27	Notch (45.45%) vs. SmM (9.09%)	0.0107 (M)
Smooth margins (SmM)	9.09	CE (90.91%) vs. SUVmax (31.82%)	4.9⋅10^−4 (M)
Notch	45.45	CE (90.91%) vs. SpM (40.91%)	1.7⋅10^−3 (M)
Spicules	40.91	CE (90.91%) vs. LM (27.27%)	2.6⋅10^−4 (M)
Positive CE (≥ 15 HU)		CE (90.91%) vs. IM (27.27%)	6.0⋅10^−5 (M)
CE +	90.91	CE (90.91%) vs. SmM (9.09%)	4.0⋅10^−6 (M)
Positive SUVmax (≥ 2.5)		CE (90.91%) vs. Notch (45.45%)	9.8⋅10^−4 (M)
SUVmax +	31.82	CE (90.91%) vs. Spicules (40.91%)	1.7⋅10^−3 (M)
Parameters	Mean ± SD	Hypothesis	p-value
Dmax (SUV ≥ 2.5)	18.86 ± 5.62	Dmax (SUV ≥ 2.5) vs. Dmax (SUV < 2.5)	0.0384 (T)
Dmax (SUV < 2.5)	14.27 ± 4.88

T: T-Student test; R: Pearson’s linear correlation coefficient; M: McNemar’s exact test.