Calpain Small Subunit 1 Protein in the Prognosis of Cancer Survivors and Its Clinicopathological Correlation

Table 2

Subgroup analysis of the association between Capn4 protein expression and OS.

Subgroup factor	Divided standard	No. of studies	Pooled HR	p-value	Heterogeneity
			(95% CI)		I^2 (%)
Sample size	≥ 150	6	1.78(1.42-2.14)	<0.001	17.0	0.304
	< 150	5	1.69(1.39-1.99)	<0.001	0.0	0.833
Cancer type	GI cancers	6	1.89(1.53-2.24)	<0.001	1.0	0.410
	Non-GI cancers	5	1.61(1.31-1.92)	<0.001	0.0	0.871
Analysis method	MVA	8	1.74(1.47-2.01)	<0.001	2.7	0.409
	UVA	3	1.70(1.26-2.14)	<0.001	0.0	0.813

GI: Gastrointestinal; UVA: univariate analysis; MVA: multivariate analysis; HR: hazard ratios.