Research Article
Calpain Small Subunit 1 Protein in the Prognosis of Cancer Survivors and Its Clinicopathological Correlation
Table 3
Results of the meta-analysis of Capn4 protein and clinicopathological features.
| | Parameters | Studies | Number of cases | OR (95% CI) | p-value | Heterogeneity | | (n) | I2 (%) | | Model |
| Gender
(Male vs. Female) | 9 | 1571 | 1.09(0.86-1.39) | 0.47 | 0.0 | 0.60 | Fixed | Histological grade
(G3/G4 vs. G1/G2) | 7 | 1283 | 1.16(0.90-2.23) | 0.25 | 19 | 0.29 | Fixed | Tumor depth
(T3-4 vs. T1-2) | 3 | 482 | 4.17(1.42-12.27) | 0.01 | 82 | 0.004 | Random | Venous invasion
(+ vs. -) | 4 | 821 | 2.34(1.07-5.13) | 0.03 | 83 | 0.0005 | Random | | LNM (+ vs. -) | 5 | 768 | 2.74(1.98-3.79) | <0.001 | 9 | 0.36 | Fixed | | DM (+ vs. -) | 3 | 440 | 4.02(2.14-7.57) | <0.001 | 31 | 0.23 | Fixed | Clinical stage
(III-IV vs. I-II) | 8 | 1213 | 2.87(1.94-4.26) | <0.001 | 54 | 0.03 | Random |
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LNM: lymph node metastasis; DM: distant metastasis; OR: odds ratio.
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