Review Article
Noncoding RNAs in Steroid-Induced Osteonecrosis of the Femoral Head
Table 3
lncRNAs expression profiles in steroid-induced ONFH.
| No. | Evaluation method | Sample | Dysregulation (up) | Dysregulation (down) | References |
| 1 | Microarray qRT-PCR | Human BMSCs | 181 lncRNAs | 391 lncRNAs lncRNA RP11‐154D6 | [5] |
| 2 | Microarray qRT-PCR | Human ONFH tissue | 1179 lncRNAs lncRNA NR 027293 | 3214 lncRNAs lncRNAs ENST00000565178, NR 038891, T318776 | [49] |
| 3 | Microarray qRT-PCR | Human BMSCs | 1878 lncRNAs OGFR-AS1, LOC100505817, HOTAIR, RP1-67K17.3, CTD-2006O16.2 | 1842 lncRNAs RP1-193H18.2, XXBAC-BPGBPG55C20.3, MALAT1, CTD-3080F16.3, and RUNX1-IT1 | [50] |
| 4 | Microarray qRT-PCR | Human BMECs | 73 up lncRNAp4493 | 166 down lncRNAp19376 | [22] |
|
|
Note. lncRNAs, long noncoding RNAs; ONFH, osteonecrosis of the femoral head; qRT-PCR, quantitative real-time polymerase chain reaction; BMSCs, bone marrow mesenchymal stem cells; BMECs, bone microvascular endothelial cells.
|