HLA-DQB1/DRB1 Alleles Associate with Traditional Chinese Medicine Syndrome of Chronic Hepatitis B: A Potential Predictor of Progression

Table 1

Subjects characteristics.

Variables	KYDS (n = 28)	Non-KYDS (n = 46)	HC (n = 31)	value	OR (95% CI)
Age (y)^†	37.43 ± 8.02	35.98 ± 9.75	37.48 ± 9.35	0.21	NA
Female (%)^‡	7 (25.00%)	15 (32.61%)	11 (35.50%)	0.67	NA
HBeAg-positive, n (%)^‡	11 (46.43%)	19 (47.83%)	NA	0.86	0.92 (0.35–2.40)
HBV DNA (≥2000 IU/ml, n (%)^‡	17 (60.70%)	13 (28.30%)	NA	0.01	3.53 (1.32–9.46)
TBIL (μmol/L)^§	15.55 (9.68–21.23)	13.45 (11.18–17.85)	NA	0.62	NA
ALT (μ/L)^§	51.55 (35.00–86.25)	34.50 (28.00–52.50)	NA	0.12	NA
AST (μ/L)^§	41.50 (25.25–68.50)	39.00 (22.75, 79.25)	NA	0.49	NA

KYDS, kidney yang deficiency syndrome; HC, healthy control; TBIL, total bilirubin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; NA, not available. ^†Means ± SD. ^‡Numbers and percentages. ^§Median and interquartile range. Significant values (<0.05).