HLA-DQB1/DRB1 Alleles Associate with Traditional Chinese Medicine Syndrome of Chronic Hepatitis B: A Potential Predictor of Progression

Table 3

Comparison of the frequencies of HLA-DQB1, HLA-DRB1 alleles between KYDS group and non-KYDS group.

Allele	Frequencies in KYDS Group (2n = 56)	Frequencies in non-KYDS Group (2n = 92)	OR (95% CI)	value
DQB102:01	8 (14.29%)	4 (4.35%)	4.20 (1.13–15.61)	0.04
DQB102:02	2 (3.57%)	2 (2.17%)	1.69 (0.23–12.75)	0.63
DQB103:01:01G	13 (23.21%)	18 (19.57%)	1.35 (0.52–3.49)	0.55
DQB103:02	2 (3.57%)	4 (4.35%)	0.81 (0.14–4.73)	1
DQB103:03	13 (23.21%)	22 (23.91%)	0.57 (0.23–1.38)	0.21
DQB104:01	1 (1.79%)	3 (3.26%)	0.53 (0.05–5.37)	1
DQB105:01	2 (3.57%)	1 (1.09%)	3.46 (0.30–40.06)	0.55
DQB105:02	5 (8.93%)	13 (14.13%)	0.55 (0.17–1.76)	0.31
DQB105:03:01G	2 (3.57%)	6 (6.52%)	0.51 (0.10–2.74)	0.70
DQB106:07	0 (0.00%)	0 (0.00%)	—	—
DQB106:10	0 (0.00%)	1 (0.01%)	—	—
DQB106:01	7 (0.13%)	11 (0.65%)	1.06 (0.35–3.16)	0.96
DRB104:01	0 (0.00%)	0 (0.00%)	—	—
DRB104:05	1 (1.79%)	3 (3.26%)	0.53 (0.05–5.37)	1
DRB104:06	2 (3.57%)	4 (4.34%)	0.81 (0.14–4.73)	1
DRB112:01:01G	2 (3.57%)	0 (0.00%)	—	—
DRB112:02	8 (14.29%)	11 (11.96%)	1.35 (3.89–0.47)	0.58
DRB113:02	0 (0.00%)	0 (0.00%)	—	—
DRB113:12	1 (1.79%)	1 (1.09%)	1.67 (0.10–27.75)	1
DRB114:01:01G	1 (1.79%)	9 (9.78%)	0.15 (0.02–1.28)	0.08
DRB114:04	0 (0.00%)	1 (1.09%)	—	—
DRB114:05	2 (3.57%)	1 (1.09%)	3.46 (0.30–40.06)	0.55
DRB115:01	3 (5.35%)	12 (13.04%)	0.34 (0.09–1.33)	0.11
DRB115:02	0 (0.00%)	0 (0.00%)	—	—
DRB101:01	1 (1.79%)	1 (1.09%)	1.67 (0.10–27.75)	1
DRB103:01	8 (14.29%)	4 (4.35%)	4.20 (1.13–15.61)	0.04
DRB107:01	2 (3.57%)	3 (3.26%)	1.10 (0.17–7.04)	1
DRB108:03	6 (10.71%)	9 (9.78%)	1.12 (0.35–3.58)	1
DRB109:01	13 (23.21%)	22 (23.91%)	0.95 (0.37–2.42)	1
DRB110:01	1 (1.79%)	0 (0.00%)	—	—
DRB111:01	3 (5.36%)	6 (6.52%)	0.80 (0.18–3.49)	1
DRB116:02	2 (3.57%)	5 (5.43%)	0.63 (0.11–3.49)	0.70

KYDS, kidney yang deficiency syndrome. Significant values (<0.05).