Research Article
Vitamin D Receptor Gene Polymorphism: An Important Predictor of Arthritis Development
Table 3
Genetic test of genetic variants in RA, OA and controls.
| SNPs | Genotypes | RA Frequency (P/C) | X2-value | p-value | OA Frequency (P/C) | X2-value | p-value |
| rs10735810 | CC | 0.537/0.000 | 554.05 | 0.016 | 0.345/0.000 | 667.02 | 0.017 | CT | 0.373/0.036 | 0.652/0.036 | TT | 0.090/0.964 | 0.003/0.964 |
| rs7975232 | GG | 0.530/0.000 | 660.108 | 0.016 | 0.278/0.000 | 695.92 | >0.01 | GT | 0.430/0.002 | 0.699/0.002 | TT | 0.040/0.998 | 0.022/0.988 |
| rs1544410 | AA | 0.697/0.000 | 608.07 | 0.008 | 0.098/0.000 | 179.90 | 0.005 | AG | 0.213/0.000 | 0.269/0.000 | GG | 0.090/1.000 | 0.633/1.000 |
| rs731236 | AA | 0.050/0.000 | 316.24 | 0.005 | 0.000/0.000 | 699.98 | 0.015 | AT | 0.530/0.000 | 0.978/0.000 | TT | 0.420/1.000 | 0.022/1.000 |
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P= Patients; C= Control; represents significance at the 0.01 level. |