Medication-Related Osteonecrosis of the Jaws: Two Center Retrospective Cohort Studies

Figure 3

Stage III, MRONJ, with “iceberg” phenomena. (a) Small area with pus in the frontal region of the mandible. (b) OPG with significant bone destruction and sequestrum in frontal region. (c) Granulation, connective tissue with small abscess infiltrated with neutrophils, plasma cells, and lymphocytes. The necrotic masses at surface. (d) Necrotic tissue with connective tissue, neutrophils, plasma cells, and granulocytes (HE, x200)

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