Medication-Related Osteonecrosis of the Jaws: Two Center Retrospective Cohort Studies

Table 2

Crosstab between study variables and clinical outcome.

Study Variables	Clinical outcome		total
	cured/improvement, N (%)	stable/progression N (%)
Sex
Male	6 (54.5%)	5 (45.5%)	11
Female	15 (71.4%)	6 (28.6%)	21
Total	21 (65.6%)	11 (34.4%)	32
Age
<50 years	3 (60%)	2 (40%)	5
> 50 years	18 (66.7%)	9 (33.3%)	27
Underlying disease
Osteoporosis	8 (72.7%)	3 (27.3%)	11
Malignant	13 (61.9%)	8 (38.1%)	21
Stage
I	4 (80%)	1 (20%)	5
II	12 (66.7%)	6 (33.3)	18
III	5 (55.6%)	4 (44.4%)	9
BPs consumption
<12 months	4 (80%)	1 (20%)	5
12 to 36	11 (61.1%)	7 (38.9%)	18
>36 months	6 (66.7%)	3 (33.3%)	9
BPs intake
IV+(IV+PO)	16 (61.5%)	10 (38.7%)	26
PO	5 (83.3%)	1 (16.7%)	6
(IV+PO) +PO	9 (81.8%)	2 (18.2)	11
IV	12 (57.1%)	9 (42.9%)	21
TIMING OF TOOTH EXTRACTION
During BPs therapy	16 (69.6%)	7 (30.4%)	23
After cessation of BPs therapy	5 (55.6%)	4 (44.4%)	9
Chemotherapy
Yes	11 (64.7%)	6 (35.3%)	7
No	2(50%)	2(50%)	4
Bone metastasis
Yes	9 (64.3%)	5 (35.7%)	14
No	4 (57.1%)	3 (42.9%)	7
Localisation
mandible	15 (65.2%)	8 (34.8%)	23
maxilla	6 (66.7%)	3 (33.3%)	9
Etiology
dental extraction-trauma	20 (66.6%)	10 (33.4%)	30
No dental extraction	1 (50 %))	1 (50%)	2
Surgical approach
Surgical	10 (55.6%)	8 (44.4%)	18
Conservative	11 (78.6%)	3 (21.4%)	14

(i) Data presented as n (%) or mean ± standard deviation.