The Protective Effect of Bosentan against Atherosclerosis in Apolipoprotein E-Deficient Mice Is Mediated by miRNA-21

Figure 1

Key histological features of tissue from an ApoE^−/− mouse. Histological sections of aortic sinus tissues from control and ApoE^−/− mice were stained with hematoxylin-eosin. ApoE^−/− mice developed typical atherosclerosis of the aortic arteries in response to a high-fat diet.

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