The Protective Effect of Bosentan against Atherosclerosis in Apolipoprotein E-Deficient Mice Is Mediated by miRNA-21

Figure 3

Bosentan treatment reduced PDCD4 expression in aortic sinus tissues from ApoE^−/− mice. Immunohistochemistry staining for PDCD4 in atherosclerotic plaques from the indicated groups of mice.