Research Article

The Protective Effect of Bosentan against Atherosclerosis in Apolipoprotein E-Deficient Mice Is Mediated by miRNA-21

Figure 5

Bosentan reduced Bax expression in the aortic sinuses of ApoEāˆ’/āˆ’ mice. Immunohistochemistry staining for Bax in atherosclerotic plaques from the indicated groups of mice.