The Protective Effect of Bosentan against Atherosclerosis in Apolipoprotein E-Deficient Mice Is Mediated by miRNA-21

Figure 6

Bosentan increased Bcl-2 expression in the aortic sinuses of ApoE^−/− mice. Immunohistochemistry staining for Bcl-2 in atherosclerotic plaques from the indicated groups of mice.