The Protective Effect of Bosentan against Atherosclerosis in Apolipoprotein E-Deficient Mice Is Mediated by miRNA-21

Figure 8

Bosentan reduced the expression of PDCD4 mRNA in ApoE^−/− mice. A real-time qPCR analysis of PDCD4 mRNA expression in atherosclerotic plaques from the indicated groups of mice.