Research Article

The Protective Effect of Bosentan against Atherosclerosis in Apolipoprotein E-Deficient Mice Is Mediated by miRNA-21

Table 1

The body weights of mice in the control, ApoE−/−, and bosentan groups at baseline and after 12 weeks of treatment.

GroupNumber of animalsBody weight (g)Body weight (g)
At week 6At week 12

Control1015.98 ± 0.1928.20 ± 0.82
ApoE–/–1015.95 ± 0.2933.62 ± 0.57
ApoE–/– + bosentan1015.99 ± 0.2032.04 ± 0.72

vs. control group; vs. ApoE−/−, group; n = 10/group.