LncRNA HOXA11-AS Promotes Proliferation and Cisplatin Resistance of Oral Squamous Cell Carcinoma by Suppression of miR-214-3p Expression

Figure 6

Knockdown of HOMA11-AS enhanced CDDP-mediated tumor inhibition and regulated miR-214-3p and PIM1 in xenograft mice. TSCCA-CDDP cells infected with sh-HOMA11-AS or its negative control were injected into nude mice to establish xenograft mice. (a) Images of tumor nodes. (b) Tumor volume was measured at indicated time points (p=0.008). (c) Tumor weight was analyzed (p=0.007). (d) miR-214-3p expression in tumor tissues (p=0.021). (e) PIM1 expression in tumor tissues (p=0.034). #P < 0.05.

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