Atorvastatin Improves Hepatic Lipid Metabolism and Protects Renal Damage in Adenine-Induced Chronic Kidney Disease in Sprague-Dawley Rats

Table 1

Effect of atorvastatin treatment on general laboratory parameters after 24 days in adenine-induced CKD rats.

	CLT	CKD	CKD + ATV
Body weight (g)	380.4 ± 6.04	218.08 ± 5.22	231 ± 7.61
Average water intake (mL/day)	41.58 ± 0.59	52.91 ± 1.13	46.22 ± 0.35
Average food intake (g/day)	29.04 ± 2.24	18.78 ± 0.41	18.38 ± 0.18
Urinary volume (mL/24 h)	24.40 ± 2.21	37.00 ± 1.58	27.83 ± 2.02
L. kidney weight (g/100 g body wt)	0.43 ± 0.02	2.44 ± 0.08	1.60 ± 0.11
R. kidney weight (g/100 g body wt)	0.41 ± 0.02	2.38 ± 0.11	1.46 ± 0.12

Values represent the mean ± SEM of 5 to 6 rats (n = 5 to 6). Significant difference from control: . Significant difference from CKD: , . ATV: atorvastatin; CLT: control; CKD: chronic kidney disease.