A Novel OsteomiRs Expression Signature for Osteoblast Differentiation of Human Amniotic Membrane-Derived Mesenchymal Stem Cells

Table 1

MicroRNAs expression profile of hAMSC after 7 days of differentiation to osteoblasts.

Down-regulated	Fold change (log2)	p-value	Chromosomal location
miR-425-5p	-8.90	0.003	3p21.31
miR-223-5p	-2.53	0.023	Xq12
miR-150-5p	-2.52	0.003	19q13.33
miR-342-5p	-1.73	0.043	14q32.2
Hsa-miR-197-3p	-1.52	0.039	1p13.3
miR-99b-5p	-1.51	0.003	19q13.41
miR-219a-1-3p	-1.50	0.002	6p21.32
miR-193a-3p	-1.48	0.009	17q11.2
miR-422a	-1.48	0.009	15q22.31
miR-576-3p	-1.47	0.014	4q25
miR-423-5p	-1.46	0.003	17q11.2
miR-362-3p	-1.44	0.003	Xp11.23
miR-140-3p	-1.44	0.001	16q22.1
miR-34b-3p	-1.04	0.015	7q32.2
miR-29b-2-5p	-1.04	0.007	1q32.2
miR-335-3p	-1.01	0.010	5q33.3
miR-148b-5p	-0.99	0.001	7p15.2
mir-770-5p	-0.98	0.026	14q32.2
Up-regulated	Fold change; (log2)	p-value	Chromosomal location
miR-424-3p	1.05	0.015	Xq26.3
miR-769-5p	1.06	0.009	19q13.32
miR-19b-3p	1.51	0.010	13q31.3

miRNAs previously related to osteogenesis are denoted in bold.