In Silico and In Vitro Analysis of the 4,4′,4′′-((1,3,5-Triazine-2,4,6-triyl)tris(azanediyl))triphenol), an Antioxidant Agent with a Possible Anti-Inflammatory Function

Table 2

Molecular docking analysis for the interaction of COX-2 with the two different ligands.

Ligand	Δ Gbind (kcal mol^−1)
Quercetin	−54.2 ± 3.6
TP-derivate	−43.6 ± 2.9

Data correspond to the mean ± SE of ten best protein-ligand conformations of five independent docking runs for each ligand with the COX-2. Different superscripted letters indicate significant differences of COX-2 with the different ligands (Tukey HSD test, p = 0.05). ΔGbind, total binding energy.