Amides Derived from Vanillic Acid: Coupling Reactions, Antimicrobial Evaluation, and Molecular Docking

Table 2

Effects of amide 7 MIC against C. guilliermondii, in the presence or absence of a protective osmotic (sorbitol 0.8 M) as well as in the presence or absence of ergosterol.

Concentration (μmol/mL)	Candida guilliermondii
	(207)
	No sorbitol	With sorbitol	No ergosterol	With ergosterol
3.68	-	+	-	-
1.84	-	+	-	+
0.92	-	+	-	+
0.46	-	+	-	+
0.23	+	+	+	+
0.11	+	+	+	+
Caspofungin	0.3 μmol/mL	4.5 μmol/mL	-
Nistatin	-		0.00043 μmol/mL	0.26 μmol/mL

+:microorganism growth. -: no microorganism growth.