[Retracted] Exosomes Derived from Human Bone Marrow Mesenchymal Stem Cells Stimulated by Deferoxamine Accelerate Cutaneous Wound Healing by Promoting Angiogenesis
Figure 4
Promoted angiogenesis in the wound sites after exosomes treatment. (a) Left panel, Microfil perfusion for determination of blood vessel density in the wound sites on day 14 after wounding; right panel, quantitative analysis of blood vessel density in three groups. P < 0.001 versus control, ### P < 0.001 versus Exos group. (b) Left panel, immunohistochemical staining against CD31 of wound sections on day 14 after wounding. Scale bar = 50 μm; right panel, quantitative determination of the number of total blood vessels. P < 0.001 versus control, ### P < 0.001 versus Exos group. (c) Left panel, immunofluorescent staining against CD31 and α-SMA of wound sections from three groups on day 14 after wounding. Scale bar = 50 μm; right panel, quantitative determination of the number of mature blood vessels. P < 0.001 versus control, ### P < 0.001 versus Exos group.