PLCE1 Polymorphisms and Risk of Esophageal and Gastric Cancer in a Northwestern Chinese Population

Table 3

Haplotypes of PLCE1 and their association with EC and GC risk.

ID	Block	Haplotype	Frequency		OR	(95%CI)	Chi^2	P
			Case	Control
1	Global	CCAAGTC	71.5%	77.8%	0.72	(0.53-0.97)	4.742	0.029
2		TAGGACG	16.8%	14.6%	1.18	(0.83-1.69)	0.861	0.354
3		TAGGGTC	4.7%	2.9%	1.66	(0.83-3.28)	2.115	0.146
4		TCAAGTC	3.0%	1.2%	2.49	(0.97-6.41)	3.834	0.050
5		TCGGGTC	2.2%	1.2%	1.82	(0.66-5.03)	1.381	0.240
6	Sub-1	CCAA	72.4%	79.7%	0.67	(0.49-0.91)	6.756	0.009
7		TAGG	22.1%	17.6%	1.33	(0.96-1.84)	2.859	0.091
8		TCAA	3.0%	1.2%	2.48	(0.95-6.42)	3.752	0.053
9		TCGG	2.2%	1.2%	1.81	(0.65-5.04)	1.331	0.249
10	Sub-2	GTC	81.5%	83.2%	0.89	(0.63-1.25)	0.436	0.509
11		ACG	17.1%	14.8%	1.19	(0.83-1.70)	0.921	0.337

Notes. (A) Only haplotypes with frequencies of ≥ 3% are shown. (B) The results were in bold, if the P value < 0.05.
EC, esophageal cancer; GC, gastric cancer.