Relationship of Platelet Counts and Inflammatory Markers to 30-Day Mortality Risk in Patients with Acute Type A Aortic Dissection

Table 2

Predictive value of each biomarker and biomarker combination for 30-day mortality using univariate and multivariate Cox regression analysis.

	30-day mortality
	Univariate analysis		Multivariate analysis^&		Multivariate analysis^$
	Hazard ratio (95%)	value	Hazard ratio (95%)	value	Hazard ratio (95%)	value
Platelet count	0.997 (0.995-1.000)	0.020	0.998 (0.995-1. 001)	0.190	0.999 (0.996-1.002)	0.512
LNR	0.12 (0.03,0.58)	0.008	0.02 (0.00-0.44)	0.012	0.11 (0.01-1.72)	0.115
LMR	0.83 (0.72,0.96)	0.010	0.80 (0.65-0.98)	0.033	0.95 (0.78-1.15)	0.572
One low biomarker	1.29 (0.78-2.13)	0.323	2.35 (1.07-5.16)	0.033	2.16 (0.98-4.77)	0.058
Two low biomarkers	2.15 (1.33-3.46)	0.002	3.16 (1.45-6.91)	0.004	1.70 (0.75-3.86)	0.203
Three low biomarkers	2.60 (1.57-4.30)	<0.001	4.66 (2.04-10.66)	<0.001	2.70 (1.16-6.29)	0.021

^&adjusted for age, smoker, pulse pressure, serum creatinine, and D-dimer. ^$adjusted for age, smoker, pulse pressure, serum creatinine, D-dimer, and surgical intervention. LNR: lymphocyte to neutrophil ratio; LMR: lymphocyte to monocyte ratio.