Predicting the Incidence and Prognosis of Bone Metastatic Breast Cancer: A SEER-Based Observational Study

Table 4

Median survival time of bone metastasis cancer patients according to molecular subtype and patient characteristics.

Characteristics	Luminal A		Luminal B		HER2+		TNBC		value
	(HR+/Her2-)		(HR+/Her2+)		(HR-/Her2+)		(HR-/Her2-)
	Median	95% CI	Median	95% CI	Median	95% CI	Median	95% CI
All	19	17.724-20.276	20	16.779-23.221	10	6.887-13.113	9	7.828-10.172	<0.001
Age
<40	27	21.289-32.711	25	20.429-29.571	19	9.532-28.468	13	9.832-16.168	<0.001
40-59	24	22.144-25.856	24	19.463-28.537	12	6.792-17.208	10	8.263-11.737	<0.001
≥60	15	13.553-16.447	14	8.137-19.863	6	2.017-9.983	7	5.530-8.470	<0.001
value		<0.001		<0.001		0.177		0.003
Race
White	19	17.446-20.554	19	14.887-23.113	11	6.617-15.383	9	7.714-10.286	<0.001
Black	16	13.831-18.169	22	17.254-26.746	8	3.118-12.882	10	8.013-11.987	<0.001
Other	24	20.056-27.944	7	0-22.245	12	0-24.834	7	2.340-11.660	0.006
value		<0.001		0.594		0.422		0.971
Grade
1-2	22	20.406-23.594	19	12.275-25.725	11	4.575-17.425	8	5.613-10.387	<0.001
3-4	16	14.645-17.355	20	16.340-23.660	10	6.405-13.595	9	7.754-10.246	<0.001
value		<0.001		0.996		0.739		0.736
T stage
0-2	22	20.445-23.555	23	19.581-26.419	10	3.607-16.393	10	7.712-12.288	<0.001
3-4	17	15.409-18.591	17	11.878-22.122	10	6.933-13.067	9	7.671-10.329	<0.001
value		<0.001		0.117		0.341		0.114
N stage
0-1	18	16.455-19.545	17	12.033-21.967	9	5.656-12.344	8	6.697-9.303	<0.001
2-3	21	18.792-23.208	22	18.577-25.423	16	8.355-23.645	10	8.013-11.987	<0.001
value		0.042		0.577		0.038		0.487
Brain metastasis
No	21	19.732-22.268	21	18.027-23.973	12	7.380-16.620	9	7.731-10.269	<0.001
Yes	7	4.822-9.178	9	4.756-13.244	6	1.637-10.363	6	4.522-7.478	0.002
value		<0.001		0.003		0.002		0.001
Liver metastasis
No	22	20.623-23.377	25	22.414-27.586	11	6.905-15.095	11	9.673-12.327	<0.001
Yes	11	9.013-12.987	9	4.945-13.055	9	3.404-14.596	6	4.623-7.377	<0.001
value		<0.001		<0.001		0.008		<0.001
Lung metastasis
No	22	20.661-23.339	21	17.898-24.102	18	12.664-23.336	10	8.388-11.612	<0.001
Yes	12	10.108-13.892	14	7.818-20.182	5	2.403-7.597	7	4.663-9.337	<0.001
value		<0.001		0.081		<0.001		0.002