Predicting the Incidence and Prognosis of Bone Metastatic Breast Cancer: A SEER-Based Observational Study

Table 5

Cox multivariate analysis of overall survival in bone metastasis from breast cancer.

Characteristics	HR	95% CI	value
Age at diagnosis (continuous)	1.018	1.015-1.021	<0.001
Subtype
TNBC	Reference
Luminal A	0.533	0.444-0.641	<0.001
Luminal B	0.482	0.419-0.555	<0.001
HER2+	0.542	0.484-0.608	<0.001
Brain metastasis
No	Reference
Yes	1.686	1.479-1.922	<0.001
Liver metastasis
No	Reference
Yes	1.673	1.531-1.828	<0.001
Lung metastasis
No	Reference
Yes	1.236	1.135-1.345	<0.001
Grade
1-2	Reference
3-4	1.193	1.098-1.297	<0.001
T stage
0-2	Reference
3-4	1.169	1.079-1.266	<0.001