Research Article

Metformin’s Effects on Apoptosis of Esophageal Carcinoma Cells and Normal Esophageal Epithelial Cells: An In Vitro Comparative Study

Figure 1

Metformin inhibited the viability of ESCC cells and normal esophageal epithelial cells. EC109 cells (a) and HEECs (b) were treated with metformin at different concentrations for 24 h (c), 48 h (d), and 72 h (e). Cell viability was evaluated by CCK-8. (f) IC50 of metformin in EC109 cells and HEECs at 24 h. IC50: half maximal inhibitory concentration. Data were presented as mean ± SD (n = 3). .
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