Long Noncoding RNA LINC01207 Promotes Colon Cancer Cell Proliferation and Invasion by Regulating miR-3125/TRIM22 Axis

<div>TRIM22 is a direct target of miR-3125 in colon cancer cells. (a) Putative binding sites between TRIM22 and miR-3125 obtained from TargetScan. (b, c) Relative luciferase activity of SW480 (b) and HT-29 (c) cells after cotransfected with pmirGLO-TRIM22-wt or pmirGLO-TRIM22-mut and miR-3125 mimics or miR control. (d) qRT-PCR was used to detect relative expression of TRIM22 mRNA in SW480 and HT-29 cells after indicated transfection. (e) Relative expression of TRIM22 protein in SW480 and HT-29 cells after indicated transfection was detected by western blot analysis. (f) Quantitative analysis of western blot results. miR-3125 inh, miR-3125 inhibitor. 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BioMed Research International

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Figure 4

Figure 4: Long Noncoding RNA LINC01207 Promotes Colon Cancer Cell Proliferation and Invasion by Regulating miR-3125/TRIM22 Axis 