A High-Fat Diet Exacerbates the Course of Experimental Trypanosoma cruzi Infection That Can Be Mitigated by Treatment with Simvastatin

Figure 1

Trypanosoma cruzi increases total cholesterol, LDL, and triglycerides during acute phase of experimental infection. C5BL/6 mice were infected with VL-10 of T. cruzi and plasma used to measure total cholesterol (a), HDL cholesterol (b), LDL cholesterol (c), and triglycerides (d) using colorimetric enzymatic kits. Animals were fed with normolipid or high-fat diets and treated or not with simvastatin. White bars: uninfected animals; black bars: animals infected with T. cruzi. The data are error of the mean (SEM).

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