Qiliqiangxin Improves Cardiac Function through Regulating Energy Metabolism via HIF-1α-Dependent and Independent Mechanisms in Heart Failure Rats after Acute Myocardial Infarction

Figure 2

QL preserved myocardial structure and inhibited cardiac fibrosis via the HIF-1α-dependent pathway. (a) QL preserved the arrangement of myocardial fibers, which were obviously irregularly arranged in the MI group (20x, , /group). (b and c) QL attenuates cardiac fibrosis with decreased cardiac fibrosis compared with the MI group (10x, , /group). Data are expressed as . and compared with the sham group; ^# and ^## compared with the MI group; ^& and ^&& compared with the MI+QL group.

(a)

(b)

(c)