Research Article

Silencing of PRDX2 Inhibits the Proliferation and Invasion of Non-Small Cell Lung Cancer Cells

Figure 4

Knockdown of PRDX2 inhibits activation of the Akt/mTOR signaling pathway in NSCLC cells. (a) Following transfection of 48 h, the protein expression of Akt, p-Akt, mTOR, p-mTOR, Cyclin D1, and p70S6k in A549 and H1299 cells after si-PRDX2 or si-NC transfection. (b, c) Quantitative analysis of western blot results in A549 (b) and H1299 (c) cells. .
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