Gold Nanoparticles Enhance EGFR Inhibition and Irradiation Effects in Head and Neck Squamous Carcinoma Cells

Figure 1

(a) Enhanced Raman spectrum of AG-1478 500 nM EtOH/solution, normal Raman spectrum of solid, and citrate-capped AuNPs. (b) Enhanced Raman spectrum when the order of mixing AG-1478 500 nM EtOH/solution and AuNPs was changed from front to back. (c) Enhanced Raman spectra of AG1478 concentrations at 5 μM, 500, 150, 100, 50, and 25 nM in the measured solution. (d) [Log]–[log] plot of the SERS peak height at 1370 cm⁻¹ by concentration yielded nearly sigmoid-like calibrations in the range of 500, 150, 100, and 50 nM AG1478.

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