Gold Nanoparticles Enhance EGFR Inhibition and Irradiation Effects in Head and Neck Squamous Carcinoma Cells

Figure 3

(a) Effects of the combination of 1 nM AuNP+0.5 μM AG1478 on HNSCC cell proliferation, with or without 4 Gy irradiation. For counting, cells and their nuclei were visualized using DAPI and E-cadherin. (b) Compared with the control group and the AuNP-alone group, the other six groups all showed significantly decreased cell numbers. In addition, the 0.5 μM AG1478+1 nM AuNP+4 Gy irradiation group had significantly lower cell counts than the 1 nM AuNP+4 Gy irradiation group.

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