Prediction of Side Effects Using Comprehensive Similarity Measures

Table 1

Information on features used in this study.

Name	Description	Source
Drug-drug interactions from DrugBank (DDIs-D)	Change in the efficacy or toxicity of one drug caused by another drug	DrugBank
Drug-drug interactions from network (DDIs-N)		STRING
Single nucleotide polymorphism (SNP)	Substitution of a single nucleotide that occurs at a specific position in the genome	Fagny et al. [12]
Target protein	Functional biomolecule controlled by drugs	DrugBank
Chemical structure	A molecule represented by a graph with nodes (atoms) and edges (bonds)	DrugBank, PubChem
Indication	Use of drugs for treating particular diseases	TTD, CTD, repoDB
Side effect anatomical hierarchy	Anatomical characteristic of a side effect	Wadhaw et al. [13]