Research Article

Pressure-Controlled Ventilation-Volume Guaranteed Mode Combined with an Open-Lung Approach Improves Lung Mechanics, Oxygenation Parameters, and the Inflammatory Response during One-Lung Ventilation: A Randomized Controlled Trial

Table 2

Intraoperative characteristics.

PCV+OLA
()
PCV
()
VCV+OLA
()
VCV
()

Type of surgery
 Lobectomy21 (46.7%)24 (54.5%)25 (55.6%)23 (54.8%)0.664
 Wedge resection20 (44.4%)13 (29.5%)13 (28.9%)12 (28.6%)
 Segmentectomy4 (8.9%)7 (15.9%)7 (15.6%)7 (16.7%)
Double lumen tube
 Left/right39/642/243/239/30.331
Vasoactive drugs25 (55.6%)23 (52.3%)26 (57.8%)22 (52.4%)0.945
Volume of fluids (mL)1002.50 (922.50, 1158.54)1028.75 (925.52, 1163.00)1068.75 (902.63, 1153.65)1057.50 (917.71, 1270.94)0.685
Urine output (mL)300.00 (200.00, 500.00)275.00 (200.00, 400.00)300.00 (200.00, 400.00)300.00 (200.00, 500.00)0.401
Duration of operation (min)140.00 (100.00, 193.50)147.50 (107.50, 189.50)155.00 (107.50, 190.00)170.00 (114.25, 220.50)0.339
Duration of anesthesia (min)180.00 (140.00, 237.50)195.00 (141.25, 225.00)200.00 (145.00, 228.50)212.50 (157.50, 262.50)0.400
Duration of OLV (min)120.00 (87.50, 175.00)133.00 (96.25, 170.00)135.00 (92.50, 175.00)160.00 (100.00, 200.00)0.352
Blood loss (mL)40.00 (10.00, 50.00)40.00 (10.00, 50.00)50.00 (10.00, 50.00)50.00 (10.00, 100.00)0.489
HR
 T10.548
 T20.226
 T30.539
MAP
 T10.422
 T20.343
 T30.138

Data are expressed as (SD), numbers, or median (interquartile range). OLV: one-lung ventilation; HR: heart rate; T1: total-lung ventilation 10 min after induction; T2: one-lung ventilation 45 min; T3: total-lung ventilation 10 min after one-lung ventilation; MAP: mean arterial pressure.