Research Article

Host Genetic and Environmental Factors Shape the Composition and Function of Gut Microbiota in Populations Living at High Altitude

Table 4

Top 10 abundant COGs of the gut microbiota in native Tibetans.

#COGSum (%)Description

COG13731,412,968 (20.35)ATPase (AAA+superfamily)
NOG00099850,664 (12.25)TonB-dependent receptor plug
NOG02827780,632 (11.24)ATPase (AAA)
COG0642739,750 (10.65)Histidine kinase
COG3250654,486 (9.43)Hydrolase family 2
COG0463568,870 (8.19)Glycosyltransferase, family 2
COG1472533,440 (7.68)Hydrolase family 3
COG0793474,230 (6.83)Protease
COG0534473,946 (6.83)Mate efflux family protein
COG0745454,886 (6.55)DNA-binding response regulator, OmpR family

COG: clusters of orthologous group.