Research Article

Human Epididymis Protein 4 Levels in Neonates with Respiratory Disorder

Table 2

Serum levels of human epididymis protein 4 (HE4), C-reactive protein (CRP), and procalcitonin (PCT) in the mothers’ blood samples, umbilical cord blood samples, and neonatal blood samples collected 24 hours after the delivery. Results presented as a median and [95% confidence interval for median].

Investigated groupTTN ()Controls () value

Mothers’ HE4 levels (pmol/L)52.0 [42.8–74.8]48.7 [43.8–63.1]0.65
Umbilical HE4 levels (pmol/L)235.8 [193.9–271.1]204.5 [186.2–238.5]0.14
Neonatal HE4 levels (pmol/L)383.1 [312.8–511.7]305.4 [284.3–370.1]0.003
value<0.0001<0.001
Mothers’ CRP levels (mg/L)4.6 [3.2–6.3]5.2 [3.4–6.0]0.52
Mothers’ PCT levels (ng/mL)0.4 [0.1–0.4]0.3 [0.1–0.3]0.62
Neonatal CRP levels (mg/L)1.8 [0.9–3.1]1.3 [0.7–2.1]0.11
Neonatal PCT levels (ng/mL)0.6 [0.4–1.2]0.7 [0.5–1.4]0.45

The value from the Mann-Whitney test and Kruskal-Wallis test.