Autophagic Network Analysis of the Dual Effect of Sevoflurane on Neurons Associated with GABARAPL1 and 2

Figure 2

GO enrichment analysis of 77 proteins associated with DPTs by WebGestalt 2019. Only 50 user IDs of 77 proteins associated with DPTs were mapped to the unique Entrez Gene IDs. WebGestalt 2019 was used to evaluate the biological process (red column), cellular component (blue column), and molecular function (green column) categories (a). Among the 50 unique Entrez Gene IDs, 35 were annotated to the selected functional categories and reference list, which were used for the enrichment analysis. The bar chart shows the top 10 pathways in which 35 IDs were enriched (b). The Venn diagram shows that 7 genes in the cAMP signaling pathway, 5 genes in the GABAergic synapse, and 5 genes in the calcium signaling pathway were mapped in the gene set (c).

(a)

(b)

(c)