Accumulation of AGO2 Facilitates Tumorigenesis of Human Hepatocellular Carcinoma

<div>Bioinformatics analysis of microarray data. (a) The heat map of the pairwise comparison in control and AGO2 knockout SMMC-7721 cells. The colored bar shows the expression levels of genes. (b) Gene Ontology (GO) functional classification of differentially expressed genes (DEGs). The GO terms are shown in the bar chart of biological processes, cellular components, and molecular functions. (c) Heatmaps showed the upregulation and downregulation of DEGs associated with disease. 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-3Z"></path></g><g transform="matrix(.013,0,0,-0.013,55.665,0)"><path d="M300 253H71L57 198H286L300 253Z"></path></g><g transform="matrix(.013,0,0,-0.013,60.31,0)"><path d="M412 140C382 77 369 73 315 73H129L270 222C362 320 402 379 402 466C402 571 322 635 234 635C177 635 130 609 99 576L42 495L64 475C90 514 133 568 201 568C274 568 318 519 318 435C318 349 255 267 193 193C144 135 87 78 32 23V0H405C417 45 427 89 440 131L412 140Z"></path></g></svg> indicates that the function is significantly inhibited.</div>

BioMed Research International

fig4

Figure 4

Figure 4: Accumulation of AGO2 Facilitates Tumorigenesis of Human Hepatocellular Carcinoma 