Identification of Key Genes and Long Noncoding RNA-Associated Competing Endogenous RNA (ceRNA) Networks in Early-Onset Preeclampsia

<div>Construction of the lncRNA-miRNA-mRNA ceRNA network in placental tissues of EOPE and the control group. (a) PPI networks of the DEGs. Node size is proportional to the degree of the node itself. Edge width is proportional to the combined degree between genes. (b) lncRNA-miRNA-mRNA ceRNA network. Nodes with different colors and shapes represent different RNA types. lncRNA: long noncoding RNA; miRNA: microRNA; mRNA: messenger RNA; ceRNA: competing endogenous RNA; EOPE: early-onset preeclampsia; PPI: protein-protein interaction.</div>

BioMed Research International

fig4

Figure 4

Figure 4: Identification of Key Genes and Long Noncoding RNA-Associated Competing Endogenous RNA (ceRNA) Networks in Early-Onset Preeclampsia 