Five Novel Mutations in LOXHD1 Gene Were Identified to Cause Autosomal Recessive Nonsyndromic Hearing Loss in Four Chinese Families

Table 2

Summary of clinical data for members in hearing loss families.

Subject	Gender	Age at test (years)	Age at onset	Use of aminoglycoside	PTA (dB) right ear	PTA (dB) left ear	Level of hearing impairment
F098 I-1	Male	38	—	No	16	12.5	Normal
F098 I-2	Female	39	—	No	14	13	Normal
F098II-1	Male	14	Congenital	No	81	84	Profound
F098 II-2	Male	4	Congenital	No	76	88	Severe
F564 II-1	Female	8	Congenital	No	73	70	Severe
F564 II-2	Female	3	Congenital	No	109	100	Profound
SD1226 II-1	Male	8	Childhood	No	95	91	Profound
SD1226 II-2	Male	6	—	No	12.5	12.5	Normal
SD1391 II-1	Female	7	Congenital	No	78	77	Severe