Research Article
Anthracycline-Induced Cardiotoxicity in Breast Cancer Patients from Southern Sri Lanka: An Echocardiographic Analysis
Table 6
Analysis of the risk factors of cancer patients independently associated with cardiotoxicity (logistic regression analysis).
| Characteristics | OR | 95% CI | value |
| Age (years) | | | | 50–59 | 0.60 | 0.29–1.24 | 0.167 | 60–79 | 1.14 | 0.53–2.4 | 0.730 | BMI (kg/m2) | | | | Overweight versus normal | 4.02 | 1.97–8.23 | 0.0001 | Obese versus normal | 4.21 | 1.68–10.53 | 0.002 | Nottingham grade of cancer | | | | Grade II vs. grade I | 0.62 | 0.25–1.49 | 0.283 | Grade III vs. grade II | 1.76 | 0.71–4.36 | 0.218 | Treatment with doxorubicin | 1.80 | 0.80–4.07 | 0.158 | Diabetes mellitus | 0.72 | 0.39–1.33 | 0.292 | Dyslipidemia | 1.28 | 0.69–2.38 | 0.431 | Trastuzumab | 2.19 | 0.73–6.55 | 0.159 | Radiation | 1.33 | 1.08–1.65 | 0.006 |
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OR: odds ratio; CI: confidence interval; BMI: body mass index. was considered as the level of significance. |