Diagnostic and Prognostic Values of MANF Expression in Hepatocellular Carcinoma

Table 1

The significant changes of MANF expression in transcription level of HCC vs. normal tissues (ONCOMINE database).

Tissue types	Fold change	value	-test	References	Overexpression gene rank
HCC vs. normal	1.945	1.54-53	1.77+01	Roessler Liver 2 Statistics (Roessler et al., Cancer Res 2010/12/15)	386 of 12,624 measured genes (in top 4%)
HCC vs. normal	1.398	0.0000514	3.984	Chen Liver Statistics (Chen et al., Cancer Res 2010/12/15)	1850 of 10,802 measured genes (in top 18%)
HCC vs. normal	1.435	0.011	2.391	Roessler Liver Statistics (Roessler et al., Cancer Res 2010/12/15)	3333 of 12603 measured genes (in top 27%)
HCC vs. normal	1.482	0.122	1.236	Wurmbach Liver Statistics (Wurmbach et al., Hepatology 2007/04/01)	7466 of 19,574 measured genes (in top 39%)
HCC vs. normal	-2.279	1	-6.273	Mas Liver Statistics (Mas et al., Mol Med 2008/12/21)	12189 of 12,603 measured genes (in top 97%)

Notes: ; .