Identification of Differentially Expressed Genes and miRNAs Associated with Esophageal Squamous Cell Carcinoma by Integrated Analysis of Microarray Data
Table 1
Signaling pathway enrichment analysis of DEGs in ESCC.
Term
Count
value
Up
hsa03030:DNA replication
13
3.51-08
hsa04110:cell cycle
21
8.02-07
hsa03050:proteasome
11
2.33-05
hsa03410:base excision repair
9
9.52-05
hsa03040:spliceosome
17
3.83-04
hsa03430:mismatch repair
7
4.78-04
hsa00240:pyrimidine metabolism
14
9.29-04
hsa03420:nucleotide excision repair
8
5.35-03
hsa05222:small-cell lung cancer
11
5.50-03
hsa00480:glutathione metabolism
8
8.42-03
hsa05230:central carbon metabolism in cancer
9
8.77-03
hsa04062:chemokine signaling pathway
17
1.18-02
hsa03013:RNA transport
16
1.29-02
hsa04510:focal adhesion
17
2.83-02
hsa00230:purine metabolism
15
3.25-02
hsa04115:p53 signaling pathway
8
3.39-02
hsa04512:ECM-receptor interaction
9
4.68-02
hsa04145:phagosome
13
5.00-02
Down
hsa04810:regulation of actin cytoskeleton
11
4.23-03
hsa00260:glycine, serine, and threonine metabolism
5
4.86-03
hsa04022:cGMP-PKG signaling pathway
9
9.30-03
hsa00280:valine, leucine and isoleucine degradation
5
9.45-03
hsa00330:arginine and proline metabolism
5
1.17-02
hsa00072:synthesis and degradation of ketone bodies
