Clinical and Biological Correlates of Preoperative Cognitive Functioning of Glioma and Meningioma Patients

Table 2

Characteristics of the study sample by hsCRP and NT-proBNP tertiles.

	High-sensitivity C-reactive protein in tertiles			p	N-terminal pro-B-type natriuretic peptide in tertiles			p
	Lowest; <0.59 ml/l	Middle; 0.59-1.40 ml/l	Highest; >1.40 ml/l		Lowest; <54.10 nl/l	Middle; 54.10-163.77 nl/l	Highest; >163.77 nl/l
Gender
Male	26 (39.4)	18 (27.3)	22 (32.2)	0.15	29 (44.6)	19 (29.2)	17 (26.2)	0.04
Female	31 (29.2)	44 (41.5)	31 (29.2)		28 (26.7)	39 (36.4)	40 (37.4)
Age
Age in years	52.3 (14.6)	57.4 (14.4)	59.5 (13.5)	0.02	46.1 (13.1)	57.8 (12.2)	64.3 (11.5)	<0.01
Marital status
Living alone	14 (27.5)	22 (43.1)	15 (29.4)	0.41	13 (24.5)	19 (35.8)	21 (39.6)	0.25
With partner	43 (35.5)	40 (33.1)	38 (31.4)		44 (37.0)	39 (32.8)	36 (30.3)
Education
<=12 years	21 (31.8)	24 (36.4)	21 (31.8)	0.95	19 (29.7)	21 (32.8)	24 (37.5)	0.61
>12 years	36 (34.0)	38 (35.8)	32 (30.2)		38 (35.2)	37 (34.3)	33 (30.6)
Cardiovascular disease
No	49 (38.0)	46 (35.7)	34 (26.4)	0.03	50 (38.2)	48 (36.6)	33 (25.2)	<0.01
Yes	8 (18.6)	16 (37.2)	19 (44.2)		7 (17.1)	10 (24.4)	24 (58.5)
Functional status
KPI	83.9 (13.2)	85.2 (10.9)	86.7 (9.2)	0.43	86.9 (10.0)	84.5 (10.6)	84.6 (12.4)	0.43
Tumor side
Right	22 (28.9)	31 (40.8)	23 (30.3)	0.07	28 (36.4)	25 (32.5)	24 (31.2)	0.56
Left	32 (42.7)	20 (26.7)	23 (30.7)		25 (34.2)	25 (34.2)	23 (31.5)
Bifrontal	3 (14.3)	11 (52.4)	7 (33.3)		4 (18.2)	8 (36.4)	10 (45.5)
Tumor location
Involving frontal and/or temporal lobes	47 (35.3)	44 (33.1)	42 (31.6)	0.30	48 (36.4)	43 (32.6)	41 (31.1)	0.25
Other	10 (25.6)	18 (46.2)	11 (28.2)		9 (22.5)	15 (37.5)	16 (40.0)
Type of the tumor
I-II grade glioma	10 (40.0)	6 (24.0)	9 (36.0)	0.55	17 (68.0)	6 (24.0)	2 (8.0)	<0.01
III-IV grade glioma	23 (35.9)	23 (35.9)	18 (28.1)		21 (32.3)	22 (33.8)	22 (33.8)
Meningioma	24 (28.9)	33 (39.8)	26 (31.3)		19 (23.2)	30 (36.6)	33 (40.2)