Clinical and Biological Correlates of Preoperative Cognitive Functioning of Glioma and Meningioma Patients

Table 3

Summary of linear regression results. Relationships between hsCRB, NT-proBNP, and cognitive functioning in glioma patients in contexts of demographic and clinical variables.

	Psychomotor speed; ,			Mental flexibility; ,			Cumulative learning; ,			Delayed recall; ,			Verbal fluency; ,
		95.0% CI			95.0% CI			95.0% CI			95.0% CI			95.0% CI
hsCRB	3.90	(0.61, 7.20)	2.36	3.54	(0.02, 7.07)	2.00	-0.01	(-0.25, 0.23)	-0.10	-0.10	(-0.22, 0.03)	-1.58	-0.26	(-1.02, 0.50)	-0.68
NT-proNBP	-0.05	(-0.14, 0.03)	-1.20	-0.05	(-0.14, 0.04)	-1.14	0.00	(-0.01, 0.01)	0.27	0.00	(0.00, 0.00)	-0.03	0.01	(-0.01, 0.03)	0.81
Gender	13.12	(-17.79, 44.03)	0.85	20.43	(-12.62, 53.47)	1.23	-2.46	(-4.72, -0.20)	-2.17	-1.69	(-2.84, -0.54)	-2.93	-4.28	(-11.40, 2.84)	-1.20
Age	2.04	(0.73, 3.36)	3.09	2.47	(1.06, 3.88)	3.49	-0.12	(-0.22, -0.02)	-2.45	-0.10	(-0.15, -0.06)	-4.26	-0.43	(-0.74, -0.13)	-2.84
Education	1.28	(-31.06, 33.62)	0.08	3.83	(-30.74, 38.41)	0.22	0.24	(-2.12, 2.61)	0.21	0.09	(-1.10, 1.28)	0.15	1.82	(-5.64, 9.28)	0.49
Malignancy	11.73	(-25.85, 49.30)	0.62	39.90	(-0.27, 80.07)	1.98	-3.55	(-6.29, -0.80)	-2.57	-0.57	(-1.96, 0.82)	-0.82	-6.67	(-15.33, 1.98)	-1.54
Left/bifrontal localization	5.38	(-23.86, 34.61)	0.37	11.97	(-19.28, 43.22)	0.76	-3.68	(-5.81, -1.54)	-3.43	-2.26	(-3.34, -1.18)	-4.17	-10.52	(-17.32, -3.72)	-3.08
Frontal and/or temporal location	-21.31	(-59.32, 16.69)	-1.12	-6.26	(-46.89, 34.37)	-0.31	0.38	(-2.39, 3.16)	0.28	-0.56	(-1.96, 0.84)	-0.80	-6.33	(-15.10, 2.45)	-1.44
Functional status (KPI)	-1.88	(-2.92, -0.84)	-3.59	-1.24	(-2.36, -0.13)	-2.23	0.09	(0.01, 0.16)	2.23	0.05	(0.02, 0.09)	2.77	0.20	(-0.05, 0.45)	1.57