High Expression of UBB, RAC1, and ITGB1 Predicts Worse Prognosis among Nonsmoking Patients with Lung Adenocarcinoma through Bioinformatics Analysis

Table 2

KEGG pathways associated with the expression of UBB, RAC1, and ITGB1 using GSEA.

Gene	Name	ES	NES	NOM value	FDR value
UBB	KEGG_ribosome	0.84	2.00	≤0.001	0.012
RAC1	KEGG_ECM_receptor_interaction	0.54	1.74	0.032	0.100
	KEGG_B_cell_receptor_signaling_pathway	0.57	1.79	0.006	0.111
	KEGG_T_cell_receptor_signaling_pathway	0.49	1.64	0.026	0.132
	KEGG_toll_like_receptor_signaling_pathway	0.47	1.64	0.019	0.133
	KEGG_focal_adhesion	0.54	1.81	0.010	0.188
ITGB1	KEGG_cell_cycle	0.64	2.09	≤0.001	0.005
	KEGG_spliceosome	0.59	1.97	≤0.001	0.022
	KEGG_DNA_replication	0.59	1.82	0.018	0.056
	KEGG_RNA_degradation	0.53	1.83	≤0.001	0.066
	KEGG_mismatch_repair	0.62	1.68	0.032	0.204
	KEGG_pyrimidine_metabolism	0.43	1.65	0.010	0.232

Abbreviations: GSEA: Gene Set Enrichment Analysis; NES: normalized enrichment score; NOM: nominal; FDR: false discovery rate.