Research Article

Anemia and Kidney Function Decline among the Middle-Aged and Elderly in China: A Population-Based National Longitudinal Study

Table 1

Baseline characteristics of participants.

CharacteristicsTotal ()Nonrapid decline ()Rapid decline () value

Age (years)58.6 (8.8)57.9 (8.5)60.9 (9.2)<0.001
Male3333 (46.2)2373 (43.9)960 (53.3)<0.001
Rural residents6065 (84.1)4587 (84.8)1478 (82.0)0.016
High school education or above679 (9.4)518 (9.6)161 (8.9)0.426
PCE (yuan), median (IQR)6258.2 (3871.7, 10463.4)6137.0 (3862.3, 10283.2)6703.1 (3965.3, 10957.1)0.022
Medical insurance6849 (95.0)5150 (95.2)1699 (94.3)0.154
Current smoker2120 (29.4)1543 (28.5)577 (32.0)<0.001
Current drinker2382 (33.0)1776 (32.8)606 (33.6)0.027
Having physical examinations in the past two years5340 (74.1)3980 (73.6)1360 (75.5)0.100
BMI (kg/m2)23.6 (3.9)23.7 (3.9)23.6 (3.8)0.491
Uric acid (μmol/L)262.7 (73.5)255.7 (70.9)283.6 (77.0)<0.001
Creatinine (μmol/L)59.2 (12.2)57.7 (10.8)63.7 (14.7)<0.001
eGFR (mL/min/1.73m2)100.6 (11.1)101.9 (9.9)96.6 (13.2)<0.001
Total cholesterol (mmol/L)5.0 (1.0)5.0 (1.0)5.0 (1.0)0.397
Triglyceride (mmol/L), median (IQR)1.2 (0.8, 1.8)1.2 (0.8, 1.8)1.2 (0.9, 1.8)0.732
HDL (mmol/L)1.3 (0.4)1.3 (0.4)1.3 (0.4)0.031
LDL (mmol/L)3.0 (0.9)3.0 (0.9)3.0 (0.9)0.601
CRP (mg/L), median (IQR)1.0 (0.6, 2.1)1.0 (0.5, 2.0)1.1 (0.6, 2.3)<0.001
Hemoglobin (g/dL)14.4 (2.2)14.5 (2.2)14.3 (2.1)<0.001
Diabetes1018 (14.1)758 (14.0)260 (14.4)0.571
Hypertension2577 (35.7)1840 (34.0)737 (40.9)<0.001
CVD1005 (13.9)728 (13.5)277 (15.4)0.042
Central obesity1622 (22.5)1230 (22.7)392 (21.8)0.196
Anemia853 (11.8)585 (10.8)268 (14.9)<0.001

Note: data are (%) or mean (SD), unless stated otherwise. Abbreviations: BMI: body mass index; CRP: C-reactive protein; CVD: cardiovascular disease; eGFR: estimated glomerular filtration rate; HDL: high-density lipoprotein; IQR: interquartile range; LDL: low-density lipoprotein; PCE: personal consumption expenditure.