Research Article

Molecular Assessment of Resistance to Clarithromycin in Helicobacter pylori Strains Isolated from Patients with Dyspepsia by Fluorescent In Situ Hybridization in the Center of Iran

Table 2

Association between clarithromycin MICs and point mutations in 23S rRNA gene H. pylori.

Type of mutationNumber (%) of isolatesTotal
Low resistance no. (%)High resistance no. (%)

A2143G4 (36.4%)9 (90%)13 (62%)
A2144G5 (45.4%)1 (10%)6 (28.6%)
Undetermined2 (18.2%) 2 (9.5%)

MICs: minimum inhibitory concentrations.