Hemangiopericytoma: Incidence, Treatment, and Prognosis Analysis Based on SEER Database

Table 3

Univariate and multivariate analyses for the overall survival of hemangiopericytoma patients.

Parameter	Univariate analysis		Multivariate analysis
		HR (95% CI)		HR (95% CI)
Age	<0.001	1.04 (1.03-1.04)	0.002	1.04 (1.01-1.06)
Gender
Female	Reference
Male	0.369	0.94 (0.81-1.08)
Surgery
No	Reference		Reference
Yes	<0.001	0.38 (0.32-0.45)	<0.001	0.15 (0.05-0.41)
Chemotherapy
No	Reference		Reference
Yes	<0.001	1.88 (1.56-2.25)	0.235	1.73 (0.70-4.25)
Radiotherapy
No	Reference
Yes	0.608	0.96 (0.83-1.12)
Grade
Unknown	Reference		Reference
Well differentiated	<0.001	0.60 (0.48-0.76)	0.622	0.71 (0.18-2.76)
Moderately differentiated	0.601	0.86 (0.48-1.53)	0.122	3.50 (0.72-17.08)
Poorly differentiated	0.139	1.23 (0.93-1.63)	0.034	3.53 (1.10-11.39)
Undifferentiated	0.044	1.29 (1.01-1.64)	0.069	2.86 (0.92-8.85)
SEER historic stage
Localized	Reference		Reference
Regional	<0.001	1.49 (1.20-1.86)	0.022	2.59 (1.15-5.82)
Distant	<0.001	3.70 (2.98-4.61)	—	—
Unstaged	<0.001	1.57 (1.31-1.87)	0.229	0.25 (0.03-2.37)
AJCC stage
Unknown	Reference		Reference
I	0.621	0.74 (0.22-2.50)	0.125	0.25 (0.05-1.48)
II	0.952	1.05 (0.23-4.69)	0.292	0.32 (0.04-2.67)
III	0.055	3.28 (0.98-11.02)	0.474	0.49 (0.69-3.46)
IV	0.008	5.37 (1.56-18.49)	—	—

AJCC: American Joint Committee on Cancer; HR: hazard ratio; CI: confidence interval. was considered to be significant.