High TXLNA Expression Predicts Favourable Outcome for Pancreatic Adenocarcinoma Patients

Table 1

Univariate and multivariate analysis of OS, DFI, PFI, and DSS in patients with PAAD in the TCGA.

Parameters	Univariate analysis				Multivariate analysis
		HR	95% (lower/upper)			HR	95% (lower/upper)
OS
Age; >65 vs. ≤65	0.141	0.752	0.515	1.099
Female vs. male	0.228	0.793	0.545	1.156
Smoking history; 2/3/4/5 vs. 1	0.732	1.076	0.706	1.641
Alcohol history; Yes vs. no	0.878	1.033	0.685	1.558
Lymph node; yes vs. no	0.001	2.236	1.373	3.641	0.004	0.477	0.288	0.788
Clinical stage; III/IV vs. II/I	0.807	0.894	0.363	2.202
TXLNA expression; High vs. low	0.018	1.811	1.109	2.958	0.048	1.641	1.003	2.685
DFI
Age; >65 vs. ≤65	0.287	0.787	0.507	1.222
Female vs. male	0.661	0.908	0.591	1.396
Smoking history; 2/3/4/5 vs. 1	0.502	1.173	0.736	1.868
Alcohol history; Yes vs. no	0.382	0.810	0.504	1.300
Lymph node; Yes vs. no	0.033	0.585	0.358	0.957	0.048	0.601	0.363	0.996
Clinical stage; III/IV vs. II/I	0.328	0.561	0.176	1.786
TXLNA expression; High vs. low	0.016	1.999	1.139	3.509	0.033	1.848	1.051	3.250
PFI
Age; >65 vs. ≤65	0.159	1.318	0.897	1.937
Female vs. male	0.815	0.956	0.656	1.394
Smoking history; 2/3/4/5 vs. 1	0.786	1.059	0.7	1.602
Alcohol history; Yes vs. no	0.63	0.902	0.593	1.372
Lymph node; Yes vs. no	0.004	0.524	0.336	0.819	0.012	0.558	0.354	0.881
Clinical stage; III/IV vs. II/I	0.922	1.039	0.481	2.247
TXLNA expression; High vs. Low	0.017	1.8	1.113	2.912	0.038	1.668	1.029	2.702
DSS
Age; >65 vs. ≤65	0.640	1.115	0.706	1.762
Female vs. male	0.500	0.855	0.543	1.347
Smoking history; 2/3/4/5 vs. 1	0.463	0.827	0.498	1.373
Alcohol history; Yes vs. no	0.493	0.835	0.498	1.398
Lymph node; Yes vs. no	0.004	0.411	0.226	0.750	0.01	0.438	0.234	0.82
Clinical stage; III/IV vs. II/I	0.561	1.311	0.526	3.270
TXLNA expression; High vs. low	0.050	1.802	1.000	3.247	0.103	1.635	0.906	2.951